Quambone (population 247 and 50 dwellings) is located approximately 55 km west of Coonamble, in the Central West Region of NSW. The Village of Quambone, declared on 28 July 1894, was developed on Quambone Station. Quambone is the gateway to the Macquarie Marshes.

Merri Merri Creek runs along the western side of the village and drains a catchment area of approximately 1,330 km2 near the village. The village has experienced in excess of 12 flood events since 1950 with creek and local overland flows causing flooding in low lying areas.